Modelling health and economic outcomes in cancer
In her keynote, Veerle Coupé will discuss two micro-simulation models that focus on different parts of the disease pathway in cancer. The ASCCA model was developed to simulate the development of colorectal polyps into colorectal cancer, with the purpose to make long-term projections of health benefits and costs of different screening strategies. The MAICARE micro-simulation model was developed to predict long-term costs and health outcomes of altering diagnostics or providing individualized care in melanoma. The model consists of a description of underlying tumor growth as well as its interaction with diagnostics, treatments and surveillance. The underlying structure of both models, model assumptions and model parameterization will be discussed. In addition, use of the models to address health policy questions will be illustrated.